Safety and Immunogenicity of ND Vaccines Used in Nepal

Immunogenicity and safety of DTPw-hepatitis B combined vaccines.

INDIAN PEDIATRICS 815 VOLUME 45__OCTOBER 17, 2008 Hepatitis B virus infection is one of the major global health problems despite the availability of prophylactic vaccines. The WHO-Expanded Program on Immunization (WHO-EPI) recommends immunization of all infants against hepatitis B. The best way to achieve this goal of universal vaccination is by employing vaccine formulations combining the hepa...

Immunogenicity and Efficacy of Different Haemophilus influenzae type b Vaccines

Haemophilus influenzae, a major cause of meningitis in young children leading to death and other neurological sequelae. The disease leaves 15 to 35% of the survivors with permanent disabilities, such as, mental retardation or deafness. Despite the availability of new and more powerful antibiotics children with Hib meningitis still suffer from high mortality or morbidity. The emergence of multir...

Combined Hepatitis Vaccines Equal in Safety and Immunogenicity to Monovalent Vaccines

Reappraisal of the Immunogenicity and Safety of Three Hepatitis A Vaccines in Adolescents

Although the overall incidence of hepatitis A in Korea has been decreasing, adolescents remain highly vulnerable to its outbreaks. This study was conducted to compare the immunogenicity and safety of three hepatitis A vaccines in Korean adolescents. Healthy anti-hepatitis A virus seronegative subjects aged 13 to 19 yr were randomized in three equal groups to receive two doses of Avaxim™, Epaxal...

Testing of Novel Dengue Virus 2 Vaccines in African Green Monkeys: Safety, Immunogenicity, and Efficacy

The immunogenicity and safety of three novel host-range vaccines containing deletions in the transmembrane domain of dengue virus serotype 2 (DV2) E glycoprotein were evaluated in African green monkeys. The shorter transmembrane domains are capable of functionally spanning an insect but not a mammalian cell membrane, resulting in production of viral mutants that have reduced infectivity in mamm...